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An over-response to stress or the failure to shut down a stress response can have negative biological consequences for an individual. The brain handles (mediates) the immediate response. This response signs the adrenal medulla to release norepinephrine and epinephrine. The hypothalamus (a central area in the mind) and the pituitary gland initiate (trigger) the slower-maintenance response by signaling the adrenal cortex to release cortisol and other hormones. Many neural (nerve) circuits get excited about the behavioral response. This response raises arousal (alertness, heightened consciousness), concentrates attention, inhibits feeding and reproductive behavior, reduces pain notion, and redirects behavior.

The combined results of the three components of the strain response maintain the inner balance (homeostasis), increase energy utilization, and creation, and alter electrolyte (chemical substance elements) and liquid balance in the torso. They also tools in the organism for an instant reaction through the sympathetic, anxious system (SNS). The SNS functions by increasing the heart rate, increasing blood circulation pressure, redirecting blood flow to the heart, muscles, and brain and from the gastrointestinal tract, and releasing fuel (glucose and essential fatty acids) to help fight or flee the risk. What’s the role of the hypothalamus-pituitary-adrenal (HPA) axis (grouping) in stress?

The HPA axis is a grouping of responses to stress by the mind and the pituitary and adrenal glands. Because they control the immune system, corticosteroids in measured doses are accustomed to treat many health problems that are seen as an inflammation or an overactive disease fighting capability, such as asthma and inflammatory bowel disease. For the same reason, they are used to help reduce the chances that our body shall immunologically reject a transplanted organ. Corticosteroids can cause fluid retention and high blood pressure also. Therefore, it is important that the response to corticosteroids is carefully controlled (modulated).

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This control is usually achieved by a feedback system in which increased cortisol levels feeding back again to the hypothalamus and pituitary turn off production of ACTH. In addition, high degrees of cortisol can cause depression and psychosis extremely, which disappear when the levels return to normal. How does the response to stress work? As the complete tale is not fully known, researchers understand much about how exactly the response to stress works. Both main systems involved are the hypothalamic-pituitary-adrenal (HPA) axis and the SNS.

SNS secretes epinephrine and norepinephrine. How do the contacts in the mind work in stress? The HPA axis and the locus coeruleus systems are connected through the hypothalamus and a location of the mind known as the limbic system. The limbic system is the control area for feelings and the processing area for memory space.

These linkages are critical. For instance, if you see the bushes rustling, your locus coeruleus immediately begins things (the stress response) moving. However, when you see that it is not a hill lion but a fantastic retriever in the bush, your memory space of the tameness of the dog will switch off the strain response. Similarly, if a person is nervous before a public-speaking engagement and the first minute or two goes well, this happy feeling shall turn down the activity of the locus coeruleus.